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Synthesis of [6‐ 13 C]‐L‐lysine
Author(s) -
Sutherland Andrew,
Willis Christine L.
Publication year - 1996
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/(sici)1099-1344(199601)38:1<95::aid-jlcr816>3.0.co;2-q
Subject(s) - chemistry , lysine , enantioselective synthesis , sodium cyanide , cyanide , glutamic acid , stereochemistry , organic chemistry , combinatorial chemistry , amino acid , biochemistry , catalysis
A short and efficient enantioselective synthesis of [6‐ 13 C]‐L‐lysine from commercially available N‐benzyloxycarbonyl‐L‐glutamic acid α‐methyl ester is described using [ 13 C]‐sodium cyanide as the source of isotopic label.