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Hormesis: interpreting the β‐curve using control theory
Author(s) -
Stebbing A. R. D.
Publication year - 2000
Publication title -
journal of applied toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.784
H-Index - 87
eISSN - 1099-1263
pISSN - 0260-437X
DOI - 10.1002/(sici)1099-1263(200003/04)20:2<93::aid-jat640>3.0.co;2-7
Subject(s) - hormesis , biology , toxicology , growth curve (statistics) , adaptation (eye) , mathematics , neuroscience , econometrics , endocrinology , oxidative stress
Data from experiments exposing colonial hydroids to toxic growth inhibitors have provided evidence of growth control mechanisms that respond adaptively to counter toxic inhibition. Analysis of growth data and the development of simulation models provide an interpretation of both α‐ and β‐curves. The hypothesis also suggests that hormesis is related to adaptation by growth control mechanisms that confer tolerance to subsequent exposure. Copyright © 2000 John Wiley & Sons, Ltd.