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Toxicity of fatty acid 18:5n3 from Gymnodinium cf. mikimotoi : I. morphological and biochemical aspects on Dicentrarchus labrax gills and intestine
Author(s) -
Sola François,
Masoni Armand,
Fossat Barthélémy,
PorthéNibelle Jacqueline,
Gentien Patrick,
Bodennec Guy
Publication year - 1999
Publication title -
journal of applied toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.784
H-Index - 87
eISSN - 1099-1263
pISSN - 0260-437X
DOI - 10.1002/(sici)1099-1263(199907/08)19:4<279::aid-jat579>3.0.co;2-x
Subject(s) - dicentrarchus , gill , sea bass , mucus , osmoregulation , biology , toxicity , chemistry , biochemistry , anatomy , fishery , fish <actinopterygii> , ecology , salinity , organic chemistry
We present evidence for the toxic effects of fatty acid 18:5n3 (octadecapentaenoic acid) in the gills and intestine of the sea bass Dicentrarchus labrax . Light microscopic observation of gills showed strong mucus production and alteration of ionocytes. The Mg‐ and Na,K‐ATPase activities were inhibited, with 50 values of 10 −3 and 1.6 × 10 −4 M, respectively. Results are discussed in relation to osmoregulation. Copyright © 1999 John Wiley & Sons, Ltd.