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Hexavalent chromium‐induced congenital abnormalities in chick embryos
Author(s) -
Qureshi Shama Noreen,
Shakoori A. R.
Publication year - 1998
Publication title -
journal of applied toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.784
H-Index - 87
eISSN - 1099-1263
pISSN - 0260-437X
DOI - 10.1002/(sici)1099-1263(199805/06)18:3<167::aid-jat492>3.0.co;2-8
Subject(s) - incubation , embryo , potassium dichromate , hexavalent chromium , resorption , teratology , biology , feather , in ovo , andrology , fetus , anatomy , endocrinology , pregnancy , chromium , medicine , chemistry , biochemistry , ecology , inorganic chemistry , genetics , organic chemistry , microbiology and biotechnology
The embryotoxic and teratogenic potential of hexavalent chromium was evaluated in chick embryos. Different concentrations of aqueous solution of potassium dichromate ranging from 1.00 to 100.00 μg per egg were injected into chick eggs before incubation. A dose‐dependent embryonic mortality was observed in all the groups examined on days 7 and 14 of incubation. The following malformations were observed in survivors: reduced body size and organs; microphthalmia; micromelia; everted viscera; abnormal and twisted neck, beak and spinal cord; isolated epicarditis; club foot; haemorrhage; and patchy feathers. Total mortality showing embryonic resorption was noted in higher dose groups (25–100 μg per egg) on day 14 of incubation. © 1998 John Wiley & Sons, Ltd.