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Biological Monitoring of Occupational Exposure to Isoflurane by Measurement of Isoflurane Exhaled Breath
Author(s) -
Prado Celia,
Antonio Tortosa J.,
Ibarra Isidro,
Luna Aurelio,
Periago J. Francisco
Publication year - 1997
Publication title -
journal of applied toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.784
H-Index - 87
eISSN - 1099-1263
pISSN - 0260-437X
DOI - 10.1002/(sici)1099-1263(199705)17:3<179::aid-jat425>3.0.co;2-y
Subject(s) - isoflurane , exhaled air , cartridge , occupational exposure , environmental chemistry , chemistry , chromatography , thermal desorption , environmental science , anesthesia , desorption , medicine , toxicology , adsorption , emergency medicine , biology , materials science , metallurgy , organic chemistry
The relationship between isoflurane environmental concentrations in operating rooms and the corresponding isoflurane concentration in the exhaled air of the operating personnel at the end of the exposure has been investigated. Isoflurane was retained in an adsorbent cartridge and after thermal desorption the concentration was estimated by gas chromatography. Significant correlation between environmental and exhaled air isoflurane concentrations allowed the establishment of a biological exposure index and biological exposure limits corresponding to proposed atmospheric threshold values. © 1997 John Wiley & Sons, Ltd.