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CEREBRAL CHANGES IN OLD AGE DEPRESSION: A CASE REPORT WITH FINDINGS ON SINGLE PHOTON EMISSION TOMOGRAPHY
Author(s) -
UPADHYAYA AJAY,
ABOUSALEH M. T.,
GRIME S.,
SATISH M. N.
Publication year - 1996
Publication title -
international journal of geriatric psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 129
eISSN - 1099-1166
pISSN - 0885-6230
DOI - 10.1002/(sici)1099-1166(199610)11:10<919::aid-gps417>3.0.co;2-o
Subject(s) - depression (economics) , perfusion , abnormality , single photon emission computed tomography , cerebral hypoperfusion , emission computed tomography , medicine , antidepressant , psychiatry , persistence (discontinuity) , cerebral perfusion pressure , psychology , anxiety , geotechnical engineering , engineering , economics , macroeconomics
An 82‐year‐old woman with no past psychiatric history developed a depressive illness from which she recovered within 2 months of initiating antidepressant therapy. She underwent single photon emission computerized tomography (SPET) when depressed and subsequently 3 and 8 months after complete clinical recovery. Impaired cerebral perfusion evident during the depressed phase improved with clinical recovery, suggesting that the impaired perfusion accompanying the depressed state is partly a state dependent abnormality. However, the possibility of persistence of such impairment beyond clinical recovery cannot be ruled out.