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Acute pancreatitis associated with clothiapine use
Author(s) -
Francobandiera Giorgio,
Rondalli Giovanna,
Telattin Pierluigi
Publication year - 1999
Publication title -
human psychopharmacology: clinical and experimental
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.461
H-Index - 78
eISSN - 1099-1077
pISSN - 0885-6222
DOI - 10.1002/(sici)1099-1077(199904)14:3<211::aid-hup87>3.0.co;2-3
Subject(s) - pancreatitis , medicine , valproic acid , risperidone , metronidazole , gastroenterology , antibiotics , psychiatry , schizophrenia (object oriented programming) , chemistry , biochemistry , epilepsy
It has been found that administration of drugs such as azathioprin, sulfonamides, chlorothiazides, furosemide, estrogens, tetracycline, valproic acid and l ‐asparaginase can be associated with the onset of pancreatitis. A less convincing, but possible correlation is suspected also for chlorthalidone, ethacrynic acid, corticosteroids, procainamide, phenformin, cimetidine, metronidazole, salicylates, methyldopa and iatrogenic hypercalcemia (Dobrilla et al ., 1985; Mallory and Kern, 1980; Underwood & Frye, 1993), and atypical neuroleptics clozapine (Martin, 1992; Jubert, 1995), and risperidone (Berent et al ., 1997). We did not find any report on MEDLINE about clothiapine‐induced pancreatitis. We would like to present the case of a patient who developed a drug‐induced pancreatitis while she was treated with clothiapine, a dibenzoxazepine derivative and widely used neuroleptic. Copyright © 1999 John Wiley & Sons, Ltd.