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The synthesis of (2 R ,3 R )‐3‐( L ‐Aspartylamino)‐1‐[(2 S ,3 R )‐3‐methyl‐2‐norbornyl]‐2‐butanol, An excellent sweetener
Author(s) -
Yuasa Yoshifumi,
Nagakura Akira,
Tsuruta Haruki
Publication year - 1996
Publication title -
flavour and fragrance journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.393
H-Index - 70
eISSN - 1099-1026
pISSN - 0882-5734
DOI - 10.1002/(sici)1099-1026(199611)11:6<327::aid-ffj600>3.0.co;2-o
Subject(s) - chemistry , 2 norbornyl cation , butanol , organic chemistry , stereochemistry , ethanol
Some l ‐aspartylnorbornylamino alcohol derivatives were synthesized as potential peptide sweeteners. Of these compounds, 3‐( l ‐aspartylamino)‐1‐(3‐methyl‐2‐norbornyl)‐2‐butanol displays an excellent sweetness potency. By further synthesis of one diastereoisomer, (2 R ,3 R )‐3‐( l ‐aspartylamino)‐1‐[(2 S ,3 R )‐3‐methyl‐2‐norbornyl]‐2‐butanol, we obtained an excellent and potent sweetener.