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Recent chromatographic and electrophoretic enantioseparations of cardiovascular drugs
Author(s) -
Bojarski Jacek,
AboulEnein Hassan Y.
Publication year - 1999
Publication title -
biomedical chromatography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 65
eISSN - 1099-0801
pISSN - 0269-3879
DOI - 10.1002/(sici)1099-0801(199905)13:3<197::aid-bmc822>3.0.co;2-t
Subject(s) - chemistry , chloroformate , chromatography , enantiomer , isothiocyanate , derivatization , ethyl chloroformate , supercritical fluid chromatography , trimethylsilyl , gas chromatography , mass spectrometry , organic chemistry
The chromatographic and electrophoretic enantiomeric separation and analysis of several clinically used cardiovascular drugs have been reviewed. Several examples of recently reported applications of enantioselective analysis and various cardiovascular agents are presented. Copyright © 1999 John Wiley & Sons, Ltd. Abbreviations used: AEKC affinity electrokinetic chromatographyCBH‐1 cellobiohydrolase 1β‐CD β‐cyclodextrinCE capillary electrophoresisChiral AGP α 1 ‐acid glycoprotein columnChyrosine‐A tyrosine‐derived CSPCSC ( S )‐10‐camphorsulfonylCSP — Chiralcel OD cellulose tris(3,5‐dimethylphenyl carbamate) chiral stationary phaseDDITC (1 S ,2 S )‐ or (1 R ,2 R ‐ N ‐](2‐isothiocyanato(cyclohexyl[‐(3,5)‐dinitrobenzoylamidemGC–MS gas chromatography–mass spectrometryGITC 2,3,4,6‐tetra‐ O ‐acetyl‐β‐ D ‐glucosyl isothiocyanateMCF ( S )‐(−)‐menthyl chloroformateMSTFA N ‐methyl(trimethylsilyl)trifluoroacetamideNAB‐C 4‐(6‐methoxy‐2‐naphthyl)‐2‐butyl chloroformateNAP‐C (−)‐2‐(6‐methoxy‐2‐naphthyl)‐1‐propyl chloroformateNAP‐IT (+)‐1‐(6‐methoxy‐2‐naphthyl)ethyl isothiocyanatePEIC 1‐phenylethylisocyanate( R,R )‐DACH‐DNB CSP ( R,R )‐dinitrobenzoyl‐diaminocyclohexane CSPSFC supercritical fluid chromatographyS‐NEIC ( S )‐(−)‐1‐(1‐naphthyl)ethyl isocyanate.