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Direct resolution of enantiomers by impregnated TLC
Author(s) -
Bhushan R.,
Martens J.
Publication year - 1997
Publication title -
biomedical chromatography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 65
eISSN - 1099-0801
pISSN - 0269-3879
DOI - 10.1002/(sici)1099-0801(199709)11:5<280::aid-bmc697>3.0.co;2-u
Subject(s) - chemistry , reagent , enantiomer , resolution (logic) , chromatography , thin layer chromatography , organic chemistry , artificial intelligence , computer science
Direct resolution of enantiomers has acquired greater analytical importance. Of various chromatographic techniques, TLC continues to enjoy considerable reputation for the purpose. The present paper deals with an important and yet less explored aspect of TLC i.e. impregnation. Methods of impregnation of thin layer material with a variety of reagents and the role of impregnating reagents in resolving compounds on these layers, with special reference to main/basic approaches of impregnation as applied to direct enantiomeric resolution, are discussed. © 1997 John Wiley & Sons, Ltd.