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Postcolumn Chemiluminescence as a Detection Technique in the Liquid Chromatographic Analysis of Beta‐lactam Ring Containing Compounds
Author(s) -
Miyawa J. H.,
Schulman S. G.,
Perrin J. H.
Publication year - 1997
Publication title -
biomedical chromatography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 65
eISSN - 1099-0801
pISSN - 0269-3879
DOI - 10.1002/(sici)1099-0801(199707)11:4<224::aid-bmc677>3.0.co;2-v
Subject(s) - chemiluminescence , chemistry , luminol , chromatography , lactam , ring (chemistry) , beta lactam , organic chemistry , biochemistry , antibiotics
A broad range of compounds containing the beta‐lactam ring were screened for enhancement of luminol chemiluminescence. A selection of these compounds were found to enhance the chemiluminescence of luminol. A high‐performance liquid chromatographic method for the analysis of some beta‐lactams employing postcolumn chemiluminescence was developed via flow injection analysis studies. © 1997 John Wiley & Sons, Ltd.