Premium
Analytical Chemistry and Biochemistry of D ‐Amino Acids
Author(s) -
Imai Kazuhiro,
Fukushima Takeshi,
Santa Tomofumi,
Homma Hiroshi,
Hamase Kenji,
Sakai Kumiko,
Kato Masaru
Publication year - 1996
Publication title -
biomedical chromatography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 65
eISSN - 1099-0801
pISSN - 0269-3879
DOI - 10.1002/(sici)1099-0801(199611)10:6<303::aid-bmc624>3.0.co;2-b
Subject(s) - chemistry , derivatization , diastereomer , chromatography , amino acid , reagent , gas chromatography , high performance liquid chromatography , organic chemistry , biochemistry
The methodologies for the analysis of D ‐amino acids in biological materials have been reviewed, including the use of enzymes, gas and liquid chromatography with chiral stationary phases and diastereomer derivatization with chiral reagents followed by GC or HPLC separation. The distribution of D ‐amino acids in the body, their origin, metabolism and possible roles in human diseases are discussed.