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Synthesis and spectroscopic studies of organotin(IV) complexes of biologically active Schiff bases derived from sulpha drugs
Author(s) -
Singh Har Lal,
Varshney S.,
Varshney A. K.
Publication year - 2000
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/(sici)1099-0739(200004)14:4<212::aid-aoc980>3.0.co;2-h
Subject(s) - chemistry , biological activity , spectral properties , stereochemistry , nuclear magnetic resonance spectroscopy , combinatorial chemistry , organic chemistry , computational chemistry , biochemistry , in vitro
The reaction of dibutyltin oxide with Schiff bases derived from sulpha drugs in 1:1 molar ratio leads to the formation of a new series of organotin(IV) complexes. An attempt has been made to probe their structure on the basis of UV, IR, NMR ( 1 H, 13 C and 119 Sn) and Mössbauer spectral studies. A few representative compounds have also been screened for bactericidal activity and found to be quite active in this respect. Copyright © 2000 John Wiley & Sons, Ltd.