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Organotin gibberellates: Synthesis, spectroscopic characterization and antitumour activity
Author(s) -
Gielen Marcel,
Dalil Hassan,
Mahieu Bernard,
Biesemans Monique,
Willem Rudolph
Publication year - 1998
Publication title -
applied organometallic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 71
eISSN - 1099-0739
pISSN - 0268-2605
DOI - 10.1002/(sici)1099-0739(199812)12:12<855::aid-aoc807>3.0.co;2-x
Subject(s) - chemistry , in vitro , characterization (materials science) , stereochemistry , cell culture , combinatorial chemistry , biochemistry , nanotechnology , materials science , biology , genetics
The synthesis and characterization of di‐n‐butyl‐, tri‐n‐butyl‐ and triphenyltin gibberellates are reported. Their antitumour activities in vitro against a panel of seven human tumour cell lines are given and compared with those of drugs used clinically. Copyright © 1998 John Wiley & Sons, Ltd.