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A New Route to 2,7‐ and 7‐Functionalized Labdanes
Author(s) -
Hersel Ulrich,
Steck Melanie,
Seifert Karlheinz
Publication year - 2000
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/(sici)1099-0690(200004)2000:8<1609::aid-ejoc1609>3.0.co;2-2
Subject(s) - chemistry , carvone , total synthesis , stereochemistry , combinatorial chemistry , essential oil , limonene , chromatography
A new route for the synthesis of 2,7‐ and 7‐functionalized labdanes starts from ( R )‐carvone ( 1 ). 11‐Nordrim‐7‐en‐9‐one ( 15 ) is an appropriate starting material for the total synthesis of hispanone ( 21 ), a biologically active furolabdane isolated from the Mediterranean medicinal plant Ballota saxatilis .