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A Convenient Synthesis of 2,2‐Diallylated Nitrogen Heterocycles by Allylboration of Lactams
Author(s) -
Bubnov Yuri N.,
Pastukhov Fedor V.,
Yampolsky Ilia V.,
Ignatenko Anatoli V.
Publication year - 2000
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/(sici)1099-0690(200004)2000:8<1503::aid-ejoc1503>3.0.co;2-7
Subject(s) - chemistry , boranes , allylic rearrangement , nitrogen , lactam , beta lactam , organic chemistry , combinatorial chemistry , catalysis , boron , antibiotics , biochemistry
Lactams containing an N‐H bond are smoothly transformed into 2,2‐diallylated nitrogen heterocycles on heating with allylic boranes in THF followed by deboronation