Premium
Synthesis of Highly Soluble Annelated Polypyridines
Author(s) -
Bejan Elena,
Fontenas Christophe,
AïtHaddou Hassan,
Daran JeanClaude,
Balavoine Gilbert G. A.
Publication year - 1999
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/(sici)1099-0690(199910)1999:10<2485::aid-ejoc2485>3.0.co;2-8
Subject(s) - chemistry , ketone , ammonium acetate , organic chemistry , ammonium , diketone , michael reaction , catalysis , high performance liquid chromatography
Highly soluble annelated bi‐ and terpyridines were prepared in 46–60% yields by a two‐step procedure which combines the Michael addition of an enolizable cyclic ketone with an α,β‐unsaturated ketone and the cyclization of the resulting 1,5‐diketone in the presence of ammonium acetate.