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Synthesis of C‐Oligosaccharides That Mimic Their Natural O‐Analogous Immunodeterminants in Binding to Monoclonal Immunoglobulins
Author(s) -
Xin YanChao,
Zhang YongMin,
Mallet JeanMaurice,
Glaudemans Cornelis P. J.,
Sinaÿ Pierre
Publication year - 1999
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/(sici)1099-0690(199902)1999:2<471::aid-ejoc471>3.0.co;2-2
Subject(s) - chemistry , monoclonal antibody , antibody , stereochemistry , combinatorial chemistry , immunology , biology
We have stereoselectively synthesized the analogues of the methyl β‐glycosides of (1→6)‐β‐ D ‐ galacto ‐oligosaccharides (up to tetrasaccharide), in which the interglycosidic oxygen atoms are replaced by a methylene group.