Premium
1,1,2‐Triphenyl‐1,2‐ethanediol: A Host for Carboxylic Acids and Amides in Coordinatoclathrates ☆
Author(s) -
Ridder Daniel,
Wunderlich Hartmut,
Braun Manfred
Publication year - 1998
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/(sici)1099-0690(199806)1998:6<1071::aid-ejoc1071>3.0.co;2-5
Subject(s) - chemistry , hydrogen bond , carboxylic acid , diol , amide , host (biology) , stereochemistry , infrared spectroscopy , organic chemistry , molecule , ecology , biology
The chiral diols ( R )‐ and ( S )‐ 1 are found to form inclusion compounds with carboxylic acids and amides, as indicated by the relevant IR spectra. Two clathrates, ( R )‐ 1 · CH 3 CO 2 H and ( S )‐ 1 · CH 3 NHCHO have been characterized by their crystal structures. The interaction between the diol 1 , which functions as the host compound, and the guest compounds, is based on hydrogen bonds. Enantiomerically pure 1 can serve as chiral solvating agent in NMR spectroscopy.