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Synthesis and Structure Determination of Novel Chiral Imine‐Alkoxytitanium Complexes
Author(s) -
Fleischer Ralf,
Wunderlich Hartmut,
Braun Manfred
Publication year - 1998
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/(sici)1099-0690(199806)1998:6<1063::aid-ejoc1063>3.0.co;2-w
Subject(s) - chemistry , imine , moiety , chelation , ligand (biochemistry) , molar ratio , crystal structure , stereochemistry , combinatorial chemistry , organic chemistry , catalysis , receptor , biochemistry
The imines 4 containing a diphenylcarbinol moiety serve as chiral ligands in novel enantiomerically pure imine‐alkoxytitanium(IV) complexes. Depending on the molar ratio of the starting materials, imines 4 and titanium tetraisopropoxide, mono‐chelated complexes 5 or bis‐chelated complexes 6 / 7 result. The latter are formed diastereoselectively and the isomers 6 are main or exclusive products. Their ( A ) configuration is determined by a crystal‐structure analysis of 6b . The bis‐ligand complexes 6 or mixtures of 6 / 7 , which are found to be remarkably stable, are used as precursors not only for the reactive dihalo complexes 8a / 8b but also for the preparation of the mixed chloroisopropoxytitanium complex 8c .