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Conjugated Addition Reactions of Nitroalkanes with Electrophilic Alkenes in Aqueous Media
Author(s) -
Ballini Roberto,
Bosica Giovanna
Publication year - 1998
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/(sici)1099-0690(199802)1998:2<355::aid-ejoc355>3.0.co;2-2
Subject(s) - chemistry , electrophile , cationic polymerization , organic chemistry , conjugated system , michael reaction , aqueous medium , aqueous solution , green chemistry , solvent , chloride , electrophilic addition , combinatorial chemistry , reaction mechanism , catalysis , polymer
The Michael reaction of various nitroalkanes 1 with electrophilic alkenes 2 can be performed in NaOH (0.025−0.1 M), without any organic solvent. In many cases the presence of cetyltrimethylammonium chloride (CTACl), as cationic surfactant, produces better results. Good yields of the products 3 are obtained even with hindered, and functionalized starting materials.