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[(Ethylenediamine)Pt(uracilate)] 4 – A Metal Analogue of Calix[4]arene: Coordination Chemistry of Its 1,3‐Alternate Conformer towards First‐Row Transition‐Metal Ions
Author(s) -
R. Navarro Jorge A.,
Freisinger Eva,
Lippert Bernhard
Publication year - 2000
Publication title -
european journal of inorganic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 136
eISSN - 1099-0682
pISSN - 1434-1948
DOI - 10.1002/(sici)1099-0682(200001)2000:1<147::aid-ejic147>3.0.co;2-i
Subject(s) - chemistry , nucleobase , ethylenediamine , crystallography , heteronuclear molecule , metal , ligand (biochemistry) , conformational isomerism , stereochemistry , uracil , inorganic chemistry , molecule , nuclear magnetic resonance spectroscopy , organic chemistry , dna , biochemistry , receptor
The open “molecular box” [(en)Pt(U‐ N 1 , N 3 )] 4 ( 1 ) (where en = ethylenediamine, U = uracil dianion) is able to act as an efficient ligand for additional metal ions. Reactions of the 1,3‐alternate conformer of 1 with divalent metal ions result in the formation of octanuclear compounds of the general formula [(en)Pt(U‐ N 1 , N 3 , O 2 , O 4 )M] 4 X 8 [M = Cu 2+ , X = Cl ( 2a ), X = (SO 4 ) 0.5 ( 2b ), and M = Co 2+ ( 3 ), Ni 2+ ( 4 ), Zn 2+ ( 5 ) with X = (SO 4 ) 0.5 ], in which the heterometals are bound at the exocyclic oxygen atoms of the uracil nucleobases. The structurally characterized heteronuclear compounds show a 1,3‐alternate arrangement of the uracil nucleobases. Pt–M contacts are in the range 2.743(2)–2.804(2) Å; the Pt atoms act as weak σ donors to the heterometals. In spite of the high degree of positive charge associated with compounds 2a – 5 , they do not behave as hosts for anions. This is a consequence of the orientation of the four nucleobases which, in contrast to a cone arrangement, does not produce a sufficiently large cavity for the incorporation of anions.