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Exhaled nitric oxide measurements in childhood asthma: Techniques and interpretation
Author(s) -
Kissoon Niranjan,
Duckworth Laurie,
Blake Kathryn,
Murphy Suzanne,
Silkoff Philip E.
Publication year - 1999
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/(sici)1099-0496(199910)28:4<282::aid-ppul8>3.0.co;2-2
Subject(s) - exhaled nitric oxide , medicine , nitric oxide , asthma , exhalation , airway , exhaled air , exhaled breath condensate , intensive care medicine , immunology , anesthesia , spirometry , toxicology , biology
In this review, we outline the role of nitric oxide in airway inflammation in children with asthma. We also discuss the various methods reported for measuring exhaled nitric oxide and provide some insight as to the pros and cons and pitfalls of these techniques. Guidelines for measurements of exhaled nitric oxide based on our experience are provided, as well as suggestions for the use of this technique as a new “airway inflammation test.” Pediatr Pulmonol. 1999; 28:282–296. © 1999 Wiley‐Liss, Inc.