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Hemodynamic effects of high‐frequency oscillatory ventilation in children
Author(s) -
Goodman Allyson M.,
Pollack Murray M.
Publication year - 1998
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/(sici)1099-0496(199806)25:6<371::aid-ppul3>3.0.co;2-k
Subject(s) - medicine , mean airway pressure , hemodynamics , cardiac index , vascular resistance , anesthesia , ventilation (architecture) , oxygenation , cardiology , mechanical ventilation , cardiac output , high frequency ventilation , mechanical engineering , engineering
The purpose of this study was to evaluate the acute hemodynamic effects of transitioning a patient from conventional mechanical ventilation (CMV) to high‐frequency oscillatory ventilation (HFOV). Our hypothesis was that hemodynamic status would not be adversely affected by such a change. Ten pediatric patients with acute hypoxemic respiratory failure and a thermodilution pulmonary arterial catheter in place were prospectively evaluated on the transition from CMV to HFOV. Hemodynamic and respiratory data were obtained before and within 1 hour of transition to HFOV with a “high‐volume” ventilation strategy. On CMV, the mean oxygenation index of the patients was 18 ± 4. Despite increases in mean airway pressure and decreases in mean arterial pressure and systemic vascular resistance on HFOV, there was no change in pulmonary circulation variables, cardiac index, or oxygen delivery. We concluded that in pediatric patients with acute respiratory failure and unstable cardiovascular status, the transition from CMV to HFOV was not accompanied by a decrease in cardiac function or oxygen delivery. Pediatr Pulmonol. 1998; 25:371–374. © 1998 Wiley‐Liss, Inc.