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The critical first six months in cystic fibrosis: A syndrome of severe bronchiolitis
Author(s) -
Katznelson D.,
Szeinberg A.,
Augarten A.,
Yahav Y.
Publication year - 1997
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/(sici)1099-0496(199708)24:2<134::aid-ppul12>3.0.co;2-3
Subject(s) - medicine , bronchiolitis , cystic fibrosis , bronchiolitis obliterans , respiratory disease , intensive care medicine , pediatrics , respiratory system , lung , lung transplantation
The syndrome of infantile bronchiolitis in cystic fibrosis (CF) carries a high mortality. Fifteen cases of CF encountered over the past 19 years with severe bronchiolitis with onset during the first 6 months of life are described. Treatment included steroids in high doses. All patients recovered. Further progress resembled the usual natural course of CF and showed no evidence of persisting lung damage. The mechanism of this syndrome is not clear and is probably dependent on many factors involved in early lung disease in CF. The frequency of severe bronchiolitis in cystic fibrosis may not be high, but it continues to be seen in clinical practice today. Pediatr. Pulmonol. 1997; 24:134–136. © 1997 Wiley‐Liss, Inc.