Open AccessPerformance of opus immunoassays for thyroxine and beta‐human chorionic gonadotrophin in serum
Author(s) -
Murthy Vadiraja V.
Publication year - 1996
Publication title -
journal of clinical laboratory analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 50
eISSN - 1098-2825
pISSN - 0887-8013
DOI - 10.1002/(sici)1098-2825(1996)10:6<389::aid-jcla12>3.0.co;2-t
Subject(s) - immunoassay , opus , reference range , endocrinology , chemistry , radioimmunoassay , medicine , chromatography , immunology , antibody , computer science , operating system
Two representative immunoassays for measuring thyroxine and β‐subunit of human chorionic gonadotrophin in serum, using the Opus immunoassay analyzer, were evaluated by comparing them to the reference RIA for T4 and β‐HCG enzyme immunoassay. Both assays were superior in accuracy and precision than the reference methods and exhibited good linearity throughout the concentration range needed for discriminating abnormally low and elevated concentrations from the established reference ranges of thyroxine and β‐human chorionic gonadotrophin in serum. Correlation between the results of the Opus immunoassays and the reference assays for T4 and β‐HCG was very good with correlation coefficients of 0.92 and 0.98, respectively. © 1996 Wiley‐Liss, Inc.