Premium
On cyclins, oocytes, and eggs
Author(s) -
Taieb Frederic,
Thibier Catherine,
Jessus Catherine
Publication year - 1997
Publication title -
molecular reproduction and development
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.745
H-Index - 105
eISSN - 1098-2795
pISSN - 1040-452X
DOI - 10.1002/(sici)1098-2795(199711)48:3<397::aid-mrd14>3.0.co;2-t
Subject(s) - biology , cyclin , maturation promoting factor , microbiology and biotechnology , oocyte , cell cycle , cyclin dependent kinase 1 , mitosis , cyclin b , meiosis , cyclin b1 , maternal to zygotic transition , genetics , embryo , embryogenesis , zygote , cell , gene
Oocyte and egg are suitable model systems for studying cell division since meiotic maturation resembles a G2/M transition and early embryonic divisions are precisely timed and occur without zygotic transcription. The analysis of oocytes and eggs from different species provides the opportunity to understand the roles of proteins that are critical to the progression and maintenance of the cell cycle. Among them, cyclins are certainly worthy of investigation. Mitotic cyclins (cyclins A and B) are clearly implicated in meiosis and early embryonic cell cycles. More recent studies have revealed that G1‐type cyclins (cyclins E and D) could also play a role in both processes and cyclin H has been suggested to participate to CAK activity (cdc2‐activating kinase) in oocytes. The study of cyclins in oocytes and eggs clearly offer insights into their roles during the cell cycle. Mol. Reprod. Dev. 48:397–411, 1997. © 1997 Wiley‐Liss, Inc.