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Arterial crush injury causes decrease in tissue perfusion at the level of the microcirculation in skeletal muscle flap
Author(s) -
Krapohl Björn D.,
Mailänder Peter,
Siemionow Maria,
Giunta Riccardo,
Zins James E.
Publication year - 1999
Publication title -
microsurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 63
eISSN - 1098-2752
pISSN - 0738-1085
DOI - 10.1002/(sici)1098-2752(1999)19:8<364::aid-micr3>3.0.co;2-j
Subject(s) - cremaster muscle , microcirculation , medicine , perfusion , blood flow , artery , crush injury , anatomy , hemodynamics , skeletal muscle , abdominal aorta , intravital microscopy , cardiology , aorta , surgery
This study was designed to evaluate the effects of crush injuries to the feeding arteries of a muscle flap on microcirculatory haemodynamics. Eighteen male Sprague‐ Dawley rats were divided into three experimental groups for intravital microscopy of the cremaster muscle flap. Group 1 served as control. In group 2 the common iliac artery and in group 3 additionally the lower abdominal aorta was crushed with a Kocher clamp (17.4 N) over 5 min. Microcirculatory parameters (red blood cell velocity, vessel diameter, and capillary perfusion) were monitored before and 2 h after crush. In the one‐level crush group, red blood cell velocities significantly decreased by 39.17% ( P =0.046) in first order arterioles and by 32.91% ( P =0.0106) in second order arterioles. In capillary perfusion, a drop of 48.02% ( P =0.0039) was noted. In the two‐level crush group, red blood cell velocities significantly dropped over 32.06% ( P =0.0250) in first order arterioles, 35.91% ( P =0.0065) in second order arterioles, and 45.69% ( P =0.0782) in first order venules. Capillary perfusion was reduced by 20.16% ( P =0.374). Arterial crush injuries as possible thrombogenic insults may result in a significant decrease in skeletal muscle perfusion although the blood supply through the crushed supplying vessel is maintained. © 1999 Wiley‐Liss, Inc. MICROSURGERY 19:364–368 1999