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Organ transplantation in mice: Current status and future prospects
Author(s) -
Zhong Robert
Publication year - 1999
Publication title -
microsurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 63
eISSN - 1098-2752
pISSN - 0738-1085
DOI - 10.1002/(sici)1098-2752(1999)19:2<52::aid-micr2>3.0.co;2-m
Subject(s) - medicine , organ transplantation , transplantation , graft rejection , microsurgery , immunology , intensive care medicine , surgery
With the development of microsurgery and molecular biology in the 1990s, the mouse model for organ transplants has become increasingly popular. In the past 10 years, the number of studies using the mouse model has increased threefold. All the organ transplants, originally done in the rat model, can now be performed in mice with high success rates. This article reviews the development, advantages, limitations, and unique immunology of the mouse model as well as future prospects. © 1999 Wiley‐Liss, Inc. MICROSURGERY 19:52–55 1999