Premium
In vitro platelet aggregation studies in microvascular surgery research: A method in the rat model
Author(s) -
O'Shaughnessy Michael,
Anderson Gary L.,
Pierangeli Silvia,
Acland Robert D.,
Johnson Peter C.,
Peter Frank W.,
Barker John H.
Publication year - 1996
Publication title -
microsurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 63
eISSN - 1098-2752
pISSN - 0738-1085
DOI - 10.1002/(sici)1098-2752(1996)17:4<238::aid-micr12>3.0.co;2-0
Subject(s) - platelet aggregation , medicine , platelet , microvascular surgery , microsurgery , in vitro , function (biology) , thrombosis , surgery , immunology , microbiology and biotechnology , biochemistry , biology
There is now a growing awareness of the central role of platelet function in microvascular thrombosis. Platelet aggregation studies remain one of the most useful ways of studying platelet function and response to different stimuli. This brief communication highlights some of the main variables that can affect platelet aggregation in rats and emphasizes the existence of important differences in these variables compared with human platelet aggregation. © 1997 Wiley‐Liss, Inc. MICROSURGERY 17:238–242 1996