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Free jejunum transfers for functional reconstruction after tumour resections in the oral cavity and the pharynx: Changes of morphology and function
Author(s) -
Giovanoli Pietro,
Frey Manfred,
Schmid Stefan,
Flury Renata
Publication year - 1996
Publication title -
microsurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 63
eISSN - 1098-2752
pISSN - 0738-1085
DOI - 10.1002/(sici)1098-2752(1996)17:10<535::aid-micr2>3.0.co;2-p
Subject(s) - medicine , jejunum , pharynx , anastomosis , surgery , dehiscence , transplantation , microsurgery , carcinoma , pathology
Oropharyngeal reconstruction following resections for locally advanced carcinoma by free jejunum transfer was studied in 31 consecutive cases over a period of 6 years, from 1988–1994. The most common site was the hypopharynx (n = 23). Reconstruction of the tonsillar region was performed in 5 cases and of the inner lining of the mouth in 5 cases. Two patients underwent neoglottic reconstruction, creating a tracheo‐pharyngeal shunt. By use of an exteriorized jejunal segment for flap monitoring changes in morphology and function of a microvascular transferred denervated segment of jejunum could be monitored. The success rate was 94%. No evidence of fistula formation and local dehiscence were experienced in this series. Histological examinations showed some fibrotic changes 6 months after transplantation; lubrication and motility of the transplant were not severely altered. Biosynthesis, processing, and proteolytic activity of the jejunal epithelial cells were not impaired 2 weeks postoperatively. © 1997 Wiley‐Liss, Inc. MICROSURGERY 17:535–544 1996