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Alterations in skeletal muscle related to short‐term impaired physical mobility
Author(s) -
Kasper Christine E.,
Maxwell Leo C.,
White Timothy P.
Publication year - 1996
Publication title -
research in nursing and health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.836
H-Index - 85
eISSN - 1098-240X
pISSN - 0160-6891
DOI - 10.1002/(sici)1098-240x(199604)19:2<133::aid-nur5>3.0.co;2-n
Subject(s) - atrophy , muscle atrophy , skeletal muscle , soleus muscle , medicine , plantaris muscle , physical medicine and rehabilitation , endocrinology
The purpose of this investigation was to describe and compare two methods of recovery of atrophied skeletal muscle following short‐term impaired physical mobility. An animal model was used to study morphologic adaptations of atrophied soleus and plantaris muscles to the effects of 7 days of hind‐limb suspension (HS) followed by either sedentary recovery or run training during a 28‐day recovery period. Significant atrophy, demonstrated by decreased mean fiber area (MFA, in square micrometers), occurred during the 7‐day period of HS. During recovery, MFA returned to control values 14 days earlier in the sedentary compared with the trained groups. Run training following short‐term atrophy induced by HS did not result in the high levels of frank muscle damage and type IIC fibers previously reported following long‐term (28‐day) atrophy. © 1996 John Wiley & Sons, Inc.