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Application of genetics and genomics in drug development
Author(s) -
Polymeropoulos Mihael H.
Publication year - 2000
Publication title -
drug development research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.582
H-Index - 60
eISSN - 1098-2299
pISSN - 0272-4391
DOI - 10.1002/(sici)1098-2299(200001)49:1<43::aid-ddr7>3.0.co;2-v
Subject(s) - pharmacogenetics , genomics , drug , drug development , drug response , genome , disease , human genome , biology , pharmacogenomics , computational biology , genetics , gene , medicine , pharmacology , genotype
Pharmacogenetics is capitalizing on the tools of the Human Genome Project to introduce the new genomic information into drug development. The applications vary from identifying individuals at risk for a disease, to developing gene signatures of drug efficacy and adverse effects. Pharmacogenetics is a field in evolution from which significant growth is expected in the years to come. Drug Dev. Res. 49:43–45, 2000. © 2000 Wiley‐Liss, Inc.