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Cellular fibrous histiocytoma of the skin: Evidence of a clonal process with different karyotype from dermatofibrosarcoma
Author(s) -
Vanni Roberta,
Marras Susanna,
Faa Gavino,
Licheri Sergio,
Daniele Giovanni M.,
Fletcher Christopher D. M.
Publication year - 1997
Publication title -
genes, chromosomes and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.754
H-Index - 119
eISSN - 1098-2264
pISSN - 1045-2257
DOI - 10.1002/(sici)1098-2264(199704)18:4<314::aid-gcc11>3.0.co;2-g
Subject(s) - dermatofibrosarcoma protuberans , dermatofibrosarcoma , karyotype , sarcoma , biology , pathology , chromosome , medicine , genetics , gene
Recently, a distinct variant of cutaneous fibrous histiocytoma (FH) has been histologically characterized as a “cellular” subtype. This variant is often mistaken for sarcoma, including dermatofibrosarcoma protuberans. We report a case of cellular FH of the skin in which the cytogenetic analysis demonstrated a novel chromosome pattern, possibly allowing distinction from its histologic simulants. Genes Chromosom. Cancer 18:314–317, 1997. © 1997 Wiley Liss, Inc.