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Cytogenetic analysis of three primary Bellini duct carcinomas
Author(s) -
GregoriRomero M. Aurelia,
MorellQuadreny Luisa,
LlombartBosch Antonio
Publication year - 1996
Publication title -
genes, chromosomes and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.754
H-Index - 119
eISSN - 1098-2264
pISSN - 1045-2257
DOI - 10.1002/(sici)1098-2264(199603)15:3<170::aid-gcc4>3.0.co;2-#
Subject(s) - karyotype , duct (anatomy) , pathology , kidney , papillary renal cell carcinomas , biology , cytogenetics , chromosome , medicine , endocrinology , genetics , gene
Three Bellini duct carcinomas (BDC) of the kidney were cytogenetically analyzed after short‐term culture. All three had clonal chromosome abnormalities: 91–92,XXY,‐Y, +12, +12, −15, −16, −18, +mar (case I); 53, XY, +2,t(2;7)(p22;q11), +der(2)t (2;7)(p22;q11), +3, +r(3), add(5)(p15), +7, −8, +12, +17, +r(17), +20, −21 (case 2); and 44–47,X,‐Y, +9, +16, −21/46,XY. Some of the numerical abnormalities are shared with papillary renal cell carcinomas (PRCC)(+7, +12, +16, +17, and +20) but not with transitional renal cell carcinomas. The present findings support the previous notion that BDC are different from other types of RCC. Genes Chromosom Cancer 15:170–172 (1996). © 1996 Wiley‐Liss, Inc.