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Plasma concentrations of leptin in a bulimic patient
Author(s) -
Herpertz Stephan,
Blum Werner F.,
Wagner Richard,
Ritter Christiane,
Englaro Piera,
Senf Wolfgang,
Hebebrand Johannes
Publication year - 1998
Publication title -
international journal of eating disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.785
H-Index - 138
eISSN - 1098-108X
pISSN - 0276-3478
DOI - 10.1002/(sici)1098-108x(199805)23:4<459::aid-eat16>3.0.co;2-r
Subject(s) - leptin , binge eating , food intake , medicine , endocrinology , bulimia nervosa , obesity , body weight , binge eating disorder , psychology , eating disorders , psychiatry
Recently, the obese gene in the ob/ob mouse was cloned, along with its human homologue. The gene product leptin is important in the regulation of body weight. Excessive food intake during a binge might affect leptin synthesis. Alternatively, fluctuations in leptin synthesis might induce binge eating. Therefore, plasma leptin levels of a patient with bulimia nervosa were determined over a period of 48 hr in a natural setting. Amount, type, time of food intake, and binging and purging episodes were concomitantly assessed. Although binging and purging episodes were quite frequent, leptin levels remained stable and were neither related to food intake nor to binge episodes. © 1998 John Wiley & Sons, Inc. Int J Eat Disord 23: 459–463, 1998.