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Central mutation databases—A review
Author(s) -
Porter Christopher J.,
Talbot, Jr. C. Conover,
Cuticchia A. Jamie
Publication year - 2000
Publication title -
human mutation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.981
H-Index - 162
eISSN - 1098-1004
pISSN - 1059-7794
DOI - 10.1002/(sici)1098-1004(200001)15:1<36::aid-humu9>3.0.co;2-d
Subject(s) - biology , mutation , database , genetics , computational biology , gene , computer science
The Internet has been a key component in the coordination of the diverse group of scientists involved in the Human Genome Project. Nowhere has this contribution been more critical than in the maintenance and exchange of information about genetic variation and mutation. Whereas the majority of DNA sequence is generated and stored by a relatively few sites, a far greater number of researchers investigate the variations in that sequence from sites scattered worldwide. It falls to central databases to utilize the Internet to assemble data from these sites and make them available to the greater human genomic community. Hum Mutat 15:36–44, 2000. © 2000 Wiley‐Liss, Inc.