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Specific organic acids enhance the D ‐ribose productivity of a transketolase‐defective Bacillus subtilis strain
Author(s) -
De Wulf Peter,
Soetaert Wim,
Schwengers Dieter,
Vandamme Erick J.
Publication year - 1997
Publication title -
journal of chemical technology and biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.64
H-Index - 117
eISSN - 1097-4660
pISSN - 0268-2575
DOI - 10.1002/(sici)1097-4660(199711)70:3<311::aid-jctb758>3.0.co;2-8
Subject(s) - transketolase , bacillus subtilis , ribose , acetoin , strain (injury) , chemistry , biochemistry , fermentation , biology , bacteria , enzyme , genetics , anatomy
Abstract When the transketolase‐defective and D ‐ribose‐producing Bacillus subtilis strain ATCC 21951 was cultured in a medium provided with certain organic acids, a significantly enhanced D ‐ribose titre was obtained, while the production of acetoin and 2,3‐butanediol drastically decreased. Although the biochemical background of this phenomenon is not completely understood, it makes D ‐ribose synthesis more efficient and cheaper, the latter due to an easier recovery of D ‐ribose from the fermentation medium. ©1997 SCI