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Bacterial Bioconversion of Primary Aliphatic and Aromatic Alcohols into Acids: Effects of Molecular Structure and Physico‐chemical Conditions
Author(s) -
Druaux Dominique,
Mangeot Georges,
Endrizzi Anne,
Belin JeanMarc
Publication year - 1997
Publication title -
journal of chemical technology and biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.64
H-Index - 117
eISSN - 1097-4660
pISSN - 0268-2575
DOI - 10.1002/(sici)1097-4660(199702)68:2<214::aid-jctb611>3.0.co;2-s
Subject(s) - bioconversion , biotransformation , chemistry , butanol , alcohol , n butanol , butyric acid , ethanol , organic chemistry , fermentation , enzyme
The biotransformation of four alcohol substrates (butanol, 2‐methylbutanol, 3‐methylbutanol and 2‐phenylethanol) into their acids was studied using a strain of Acetobacter aceti . Bioconversion yields depended on the molecular structure of the alcohol. Biotransformation of high concentrations of alcohols was possible until the precursor reached an inhibiting concentration (3·8 g dm −3 for butanol and 3‐methylbutanol, 4·2 g dm −3 for 2‐methylbutanol). In contrast, biotransformation of 2‐phenylethanol decreased when alcohol concentration was higher than 0·3 g dm −3 . Dissolved oxygen concentrations and pH conditions of the medium were important factors in improving bioconversion. Transformation of 2‐methylbutanol into the corresponding acid was increased when dissolved oxygen partial pressure increased from 60 to 80% and regulation at pH 6 allowed an increase in the production of butyric acid from butanol. © 1997 SCI.