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Combined bioreaction and separation in a simulated counter‐current chromatographic bioreactor–separator for the hydrolysis of lactose
Author(s) -
Shieh M. T.,
Barker P. E.
Publication year - 1996
Publication title -
journal of chemical technology and biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.64
H-Index - 117
eISSN - 1097-4660
pISSN - 0268-2575
DOI - 10.1002/(sici)1097-4660(199607)66:3<265::aid-jctb503>3.0.co;2-#
Subject(s) - separator (oil production) , chromatography , lactose , chemistry , hydrolysis , bioreactor , chromatographic separation , organic chemistry , high performance liquid chromatography , thermodynamics , physics
The hydrolysis of lactose using the enzyme lactase from Aspergillus oryzae and the simultaneous separation of the products galactose and glucose was examined in a Simulated Counter‐Current Chromatographic Bioreactor–Separator (SCCR‐S) system. The system was operated in continuous and batch modes and the results obtained used to compare the performance in both modes. Mathematical modelling and computer simulation of the system operating in the continuous mode are reported.