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Genetic syndromes as potential targets for chemoprevention of colorectal neoplasia
Author(s) -
Levin Bernard
Publication year - 2000
Publication title -
journal of cellular biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 165
eISSN - 1097-4644
pISSN - 0730-2312
DOI - 10.1002/(sici)1097-4644(2000)77:34+<19::aid-jcb5>3.0.co;2-v
Subject(s) - colorectal cancer , cancer , demography , medicine , population , incidence (geometry) , disease , gynecology , oncology , gerontology , environmental health , sociology , physics , optics
Colorectal cancer is the second leading cause of cancer death in the United States (Landis et al. [1998] CA 48:6–29) and is the most common cancer in Israel (Muir et al. [1997] International Agency for Research on Cancer, Lyon, France). In the United States, it is estimated that 130,000 individuals will be diagnosed with colorectal cancer in 1999 and that 57,000 individuals will die from this disease. In Israel, approximately 2,000 individuals are diagnosed with colorectal cancer each year (Landis et al. [1998] CA 48:6–29). The incidence rate varies considerably in different population groups, viz. 21.1/100,000 among Jews born in Europe or North America, 19.3/100,000 in Jews born in Israel, 12.1/100,000 among Jews born in Africa or Asia (Muir et al. [1997] International Agency for Research on Cancer, Lyon, France). J. Cell. Biochem. Suppl. 34:19–22, 2000. © 2000 Wiley‐Liss, Inc.