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A functional‐phylogenetic system for the classification of transport proteins
Author(s) -
Saier, Milton H.
Publication year - 1999
Publication title -
journal of cellular biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 165
eISSN - 1097-4644
pISSN - 0730-2312
DOI - 10.1002/(sici)1097-4644(1999)75:32+<84::aid-jcb11>3.0.co;2-m
Subject(s) - archaea , phylogenetic tree , transporter , gene , computational biology , genome , biology , genetics , evolutionary biology
Twenty completely sequenced genomes of bacteria, archaea, and eukaryotes have been surveyed for the presence of genes encoding homologues of known solute transport proteins. These analyses and others have demonstrated the presence of nearly 250 families of sequence‐related transporters. All such proteins have been classified according to the system we call the transporter classification system of the transport commission (TC). This short summary article describes the main features of this system; the families are presented in tabular form. Detailed information concerning these families and their constituent transporters is available on our web sites. J. Cell. Biochem. Suppls. 32/33:84–94, 1999. © 1999 Wiley‐Liss, Inc.