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Potential involvement of post‐translational modifications as a mechanism modulating selective proteolysis after fertilization
Author(s) -
Imschenetzky Maria,
Puchi Marcia,
Morin Violeta,
Diaz Fredy,
Oliver M. Isabel,
Montecino Martin
Publication year - 1999
Publication title -
journal of cellular biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 165
eISSN - 1097-4644
pISSN - 0730-2312
DOI - 10.1002/(sici)1097-4644(1999)75:32+<149::aid-jcb18>3.0.co;2-#
Subject(s) - proteolysis , proteases , zygote , human fertilization , microbiology and biotechnology , chromatin , biology , mechanism (biology) , chromatin remodeling , chemistry , biochemistry , embryo , embryogenesis , genetics , enzyme , dna , philosophy , epistemology
The role of proteolysis during fertilization has been investigated only to a very limited extent as compared with its role on the control of cell cycle progression. In this report, we discuss briefly the proteases involved in fertilization, their relevance in the egg‐sperm interaction and in the chromatin remodeling that occurs before the reestablishment of the diploid condition of the zygote. We further emphasize how the post‐translational modifications of target proteins modulate these proteolytic events. J. Cell. Biochem. Suppls. 32/33:149–157, 1999. © 1999 Wiley‐Liss, Inc.