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Synthesis of a quaternary ammonium derivative of chito‐oligosaccharide as antimicrobial agent for cellulosic fibers
Author(s) -
Seong HaSoo,
Whang Hyun Suk,
Ko SohkWon
Publication year - 2000
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/(sici)1097-4628(20000628)76:14<2009::aid-app3>3.0.co;2-w
Subject(s) - depolymerization , chemistry , ammonium chloride , cellulose , oligosaccharide , nuclear chemistry , derivative (finance) , ammonium , polymer chemistry , acetic acid , chitosan , antimicrobial , chloride , organic chemistry , financial economics , economics
A derivative of chito‐oligosaccharide (COS), N‐(2‐hydroxyl)propyl‐3‐trimethyl ammonium chito‐oligosaccharide chloride (HTACC), was synthesized using a reaction of glycidyltrimethylammonium chloride (GTMAC) and COS prepared by depolymerization of a fully deacetylated chitosan. COS and HTACC were applied to the cotton fabrics with a pad‐dry‐cure process using the reaction between the hydroxyl group of cellulose and terminal aldehyde group in COS and HTACC. Their minimum inhibition concentration (MIC) was evaluated, and the antimicrobial activity and durability to laundering of cotton fabrics treated with them were compared. The complete substitution of NH 2 groups in COS with GTMAC was obtained at a 4 : 1 mol ratio of GTMAC to NH 2 in 18 h at 80°C under the presence of acetic acid. MIC values of the 1.04 DS of HTACC and COS were 50 and 400 μg/mL, respectively. A cotton fabric treated with 0.2% of HTACC and 1.8% of COS exhibited 100% reduction of bacteria. At the 50th laundering cycle, 0.3% of HTACC and 2.4% of COS indicated 100% bacterial reduction. © 2000 John Wiley & Sons, Inc. J Appl Polym Sci 76: 2009–2015, 2000