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Alternative molecularly imprinted membranes from a derivative of natural polymer, cellulose acetate
Author(s) -
Yoshikawa Masakazu,
Ooi Takashi,
Izumi JunIchiro
Publication year - 1999
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/(sici)1097-4628(19990425)72:4<493::aid-app5>3.0.co;2-u
Subject(s) - membrane , chemistry , adsorption , molecularly imprinted polymer , molecular imprinting , selective adsorption , polymer chemistry , cellulose , chiral resolution , selectivity , polymer , chromatography , organic chemistry , enantiomer , biochemistry , catalysis
Molecularly imprinted polymeric membranes were prepared from cellulose acetate (CA), of which acetyl content was 40%, by applying the alternative molecular imprinting technique. The Z ‐ d ‐Glu imprinted polymeric membranes thus obtained recognized d ‐Glu in preference to l ‐Glu from racemic Glu mixtures and vice versa. The affinity constants between Glu and the chiral recognition site for two kinds of membranes were determined to be 3.1 × 10 3 mol −1 dm 3 from the adsorption isotherm of d ‐Glu or L ‐Glu in the molecularly imprinted CA membranes. Enantioselective electrodialysis was attained with the present membranes reflecting their adsorption selectivity. d ‐Glu was preferentially permeated through the Z ‐ d ‐Glu imprinted CA membrane, whereas L ‐Glu was permeated through the Z ‐ L ‐Glu imprinted CA membrane. The present study suggests that the molecularly imprinted CA membranes are applicable to the optical resolution of racemic amino acids. © 1999 John Wiley & Sons, Inc. J Appl Polym Sci 72: 493–499, 1999