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Imparting recognition sites in poly(HEMA) for two compounds through molecular imprinting
Author(s) -
Sreenivasan K.,
Sivakumar R.
Publication year - 1999
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/(sici)1097-4628(19990314)71:11<1823::aid-app12>3.0.co;2-e
Subject(s) - molecularly imprinted polymer , molecular imprinting , imprinting (psychology) , methacrylate , molecular recognition , polymer , materials science , combinatorial chemistry , polymer chemistry , chemistry , organic chemistry , selectivity , molecule , catalysis , copolymer , biochemistry , gene
So far, molecularly imprinted polymers (MIPs) have been synthesized and evaluated as selective matrices for single components. It may be possible to impart multiple recognition sites in MIPs, which could be used as elements capable of binding more than one component. Such systems could advantageously be used in the design of sensors having the ability to sense more than one compound at a time. This communication discusses such a possibility by imprinting sites for two model compounds, namely, salicylic acid and hydrocortisone in poly(2‐hydroxy ethyl methacrylate). © 1999 John Wiley & Sons, Inc. J Appl Polym Sci 71: 1823–1826, 1999