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Polyether‐segmented nylon hemodialysis membranes. I. Preparation and permeability characteristics of polyether‐segmented nylon 610 hemodialysis membrane
Author(s) -
Seita Yukio,
Mochizuki Akira,
Agawa Mitsuhide Nak,
Takanashi Atsuhiro,
Yamashita Shuzo
Publication year - 1997
Publication title -
journal of applied polymer science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.575
H-Index - 166
eISSN - 1097-4628
pISSN - 0021-8995
DOI - 10.1002/(sici)1097-4628(19970829)65:9<1703::aid-app6>3.0.co;2-j
Subject(s) - membrane , formic acid , materials science , polymer chemistry , chemical engineering , polymer , nylon 6 , solvent , phase inversion , methanol , chemistry , chromatography , composite material , organic chemistry , biochemistry , engineering
The effect of the coagulation condition in the phase inversion method on the permeability characteristics of poly(propylene oxide) or poly(tetramethylene oxide)‐segmented nylon 610 (PPO‐Ny610 or PTMO‐Ny610) hemodialysis membranes, the stability of the membrane performance, and the mechanical strength were investigated. The polymers were dissolved in a solvent such as formic acid and methanol saturated with calcium chloride, and thus PPO‐Ny610 and PTMO‐Ny610 membranes were prepared using formic acid and a calcium chloride/methanol/water mixture as a polymer solvent and a coagulant, respectively. It is concluded that PPO‐Ny610 membrane has better permeability characteristics than PTMO‐Ny610 membrane, and possesses additional properties for hemodialysis membranes such as mechanical properties and permeability stability in the drying and sterilizing processes. Furthermore, the blood compatibilities of PPO‐Ny610 and PTMO‐Ny610 membranes were superior to regenerated cellulose membranes on the basis of the result of platelet adhesion test. © 1997 John Wiley & Sons, Inc. J Appl Polym Sci 65:1703–1711, 1997