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Gas‐phase pyrolytic reactions of N‐ethyl, N‐isopropyl, and N‐ t ‐butyl substituted 2‐aminopyrazine and 2‐aminopyrimidine
Author(s) -
AlAwadi Nouria A.,
ElDusouqui Osman M. E.,
Kaul Kamini,
Dib Hicham H.
Publication year - 2000
Publication title -
international journal of chemical kinetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.341
H-Index - 68
eISSN - 1097-4601
pISSN - 0538-8066
DOI - 10.1002/(sici)1097-4601(2000)32:7<403::aid-kin2>3.0.co;2-p
Subject(s) - chemistry , isopropyl , pyrolytic carbon , alkoxy group , medicinal chemistry , alkyl , kinetic energy , primary (astronomy) , gas phase , organic chemistry , pyrolysis , physics , quantum mechanics , astronomy
The rates of gas‐phase elimination of N‐ethyl (1), N‐isopropyl (2), N‐ t ‐butyl (3) substituted 2‐aminopyrazine and N‐ethyl (4), N‐isopropyl (5), and N‐ t ‐butyl (6) substituted 2‐aminopyrimidine have been measured. The compounds undergo unimolecular first‐order pyrolytic reactions. The relative rates of the primary:secondary;tertiary alkyl homologues at 600 K are 1:14.4:38.0 for the pyrazines and 1:20.8:162.5 for the pyrimidines, respectively. The reactivities of these compounds have been compared with those of the alkoxy analogues and with each other. Product analyses, together with the kinetic data, were used to outline a feasible pathway for the elimination reaction of the compounds under study. © 2000 John Wiley & Sons, Inc. Int J Chem Kinet 32: 403–407, 2000