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Spontaneous hydrolysis of ethyl formate: Isobaric activation parameters
Author(s) -
MataSegreda J. F.
Publication year - 2000
Publication title -
international journal of chemical kinetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.341
H-Index - 68
eISSN - 1097-4601
pISSN - 0538-8066
DOI - 10.1002/(sici)1097-4601(2000)32:1<67::aid-jck8>3.0.co;2-m
Subject(s) - chemistry , hydrolysis , isobaric process , autocatalysis , ethyl formate , catalysis , formate , ethyl acetate , activation energy , medicinal chemistry , organic chemistry , thermodynamics , physics
Ethyl formate undergoes spontaneous autocatalytic hydrolysis via water catalyzed (neutral), as well as hydrogen‐ion catalyzed mechanisms. The activation parameters for the neutral reaction are ΔH‡ = 91 ± 8 kJ/mol and ΔS‡ = −48 ± 8 J K −1 /mol. This result is in contrast to the values reported in the hydrolyses of the more polar activated haloesters. The specific rate of neutral hydrolysis of ethyl acetate can also be predicted. © 2000 John Wiley & Sons, Inc. Int J Chem Kinet 32: 67–71, 2000