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Kinetics of oxidation of certain pyrimidines by Ce(IV)
Author(s) -
Lakshmi S.,
Renganathan R.
Publication year - 1996
Publication title -
international journal of chemical kinetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.341
H-Index - 68
eISSN - 1097-4601
pISSN - 0538-8066
DOI - 10.1002/(sici)1097-4601(1996)28:10<713::aid-kin1>3.0.co;2-q
Subject(s) - chemistry , uracil , pyrimidine , kinetics , thymine , aqueous solution , rate equation , first order , computational chemistry , photochemistry , stereochemistry , biochemistry , dna , physics , mathematics , quantum mechanics
The kinetics of the oxidation of certain biologically important pyrimidine bases (Uracil, Thymine, and 6‐Methyluracil) by Ce(IV) in aqueous H 2 SO 4 has been investigated. A first‐order dependence of rate each on [Ce(IV)], [pyrimidine], and an inverse first‐order dependence on [H 2 SO 4 ] has been observed. Rate and activation parameters for the oxidation of these pyrimidines have been computed. A suitable rate law and a mechanism consistent with the kinetic observations and product analysis have been proposed. © 1996 John Wiley & Sons, Inc.